Oncology: The Long And Winding Trail To Cancer

[skyhigh]

Two new mouse studies have provided insight into the role of the death-inducing protein TRAIL and its receptors in tumor development and metastasis. Binding of TRAIL to its receptors induces the cells expressing the receptors to undergo a form of cell death known as apoptosis. Scientists found that if lymphoma-prone mice were deficient in the TRAIL receptor they developed lymphoma more frequently than TRAIL receptor--sufficient lymphoma-prone mice.

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